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Juan Ponce de Leon is today remembered as a explorer who operated in central American waters shortly after Christopher Columbus made his historic journey to the west. During his life De Leon made many notable achievements, but today he is mostly remembered for his colonization of Florida and its exploration.
Knowledge of 16th century Caribbean island Cuba (then known as Hispaniola) expanded greatly with the discoveries of Spanish captain Sebastián de Ocampo who successfully managed to circumvent this island for the first time and enter the gulf of Mexico.
Pedro de Alvarado is today remembered as one of the most important Spanish conquistadors who was involved in several military campaigns in Central America, including Mexico, Guatemala, Honduras, El Salvador and the downfall of the Aztec culture.
One of the most famous Spanish explorers of 16th century was Hernando de Soto, who accompanied conquistador Francisco Pizarro in his destruction of Incan empire and contributed to the modern history by exploring the lands of Florida and discovering the mighty river Mississippi.